Across TCGA patient cohorts, OPALIN protein abundance is significantly associated with the RNA expression of many other genes, with 1,737 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPALIN-associated genes across cancer lineages are SOX10, PICK1, and SLC16A8. Each is linked with OPALIN in more than 1 cancer types. Because this analysis shows association rather than direction, both OPALIN-to-partner and partner-to-OPALIN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPALIN→partner) and Y-score (partner→OPALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+1.802	+0.981	<.001	<.001	3	1
GBM	PICK1 →	+0.500	+1.186	<.001	<.001	3	1
GBM	SLC16A8 →	+0.483	+0.805	<.001	<.001	3	1
GBM	SUN2 →	+0.360	+0.666	<.001	<.001	3	1
GBM	RASL10A →	+0.682	+0.682	<.001	<.001	3	1
GBM	NEFH →	+0.792	+0.698	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,737 associations by consensus.

Exploration

OPALIN survival (RNA) · tumor vs normal (RNA) · all OPALIN data types