OPALIN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OPALIN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,302 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OPALIN-associated GO terms across cancer lineages are Regulation of vesicle docking, Regulation of transcription by RNA polymerase I, and Mitotic telomere maintenance via semi-conservative replication. Each is linked with OPALIN in more than 3 cancer types. Because this analysis shows association rather than direction, both OPALIN-to-partner and partner-to-OPALIN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OPALIN→partner) and Y-score (partner→OPALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaRegulation of vesicle docking →-0.203-0.675<.001<.00134
BREASTRegulation of transcription by RNA polymerase I →+0.079+0.002.003.00733
LUNG_SCLCMitotic telomere maintenance via semi-conservative replication →+0.080+0.004<.001.00333
LUNG_SCLCGlycosaminoglycan biosynthetic process →+0.077+0.008.001.00933
BLOOD_LeukemiaRegulation of calcium ion transport into cytosol →-0.137-0.400<.001<.00133
BLOOD_LeukemiaChromatin looping →+0.041+0.532.008.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,302 associations by consensus.

Exploration