OOSP4B

Across TCGA pan-cancer cohorts, OOSP4B RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated OOSP4B data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher OOSP4B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OOSP4B expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

KIRP, UCEC, and LIHC are the cancer types where OOSP4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.181	0.728	<.001	141	view →
UCEC	OS	Tertile	All	0.757	0.929	.002	120	view →
LIHC	DFS	Tertile	II,III,IV	0.066	0.420	<.001	72	view →
KIRC	DFS	Tertile	All	0.197	0.656	<.001	66	view →
ESCA	OS	Tertile	III,IV	1.000	0.358	.012	42	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	42	view →
CESC	DFS	Tertile	II,III,IV	0.140	0.785	<.001	36	view →
PCPG	DFS	Tertile	All	0.079	0.774	<.001	36	view →
GBM	OS	Tertile	All	0.005	0.416	<.001	27	view →
SARC	OS	Tertile	All	0.648	0.843	.002	21	view →
BLCA	OS	Tertile	IV	0.237	0.598	.004	18	view →
STAD	DFS	Tertile	All	0.474	0.728	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

OOSP4B–KIRP (OS)

Open the KIRP breakdown →