OOSP4A

Across TCGA cell cohorts, OOSP4A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,128 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OOSP4A-associated GO terms across cancer lineages are Negative regulation of response to endoplasmic reticulum stress, Ribosome assembly, and Protein transmembrane transport. Each is linked with OOSP4A in more than 4 cancer types. Because this analysis shows association rather than direction, both OOSP4A-to-partner and partner-to-OOSP4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to endoplasmic reticulum stress grouped by OOSP4A-low versus OOSP4A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OOSP4A→partner) and Y-score (partner→OOSP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of response to endoplasmic reticulum stress →	+0.044	+0.444	.001	.001	3	5
BLOOD_Leukemia	Ribosome assembly →	+0.052	+0.402	.001	.006	3	4
BLOOD_Leukemia	Protein transmembrane transport →	+0.024	+0.415	.001	.003	3	4
LARGE_INTESTINE	Cellular component assembly involved in morphogenesis →	-0.052	-0.050	<.001	<.001	3	4
LARGE_INTESTINE	Cellular anatomical entity morphogenesis →	-0.052	-0.050	<.001	<.001	3	4
OVARY	Negative regulation of glial cell proliferation →	+0.107	+0.019	.008	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,128 associations by consensus.

Negative regulation of response to endoplasmic reticulum stress by OOSP4A expression — BLOOD_Leukemia

Explore this box plot interactively →