OOSP3

Across TCGA cell cohorts, OOSP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,121 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OOSP3-associated GO terms across cancer lineages are Double-strand break repair via homologous recombination, Regulation of embryonic development, and Spliceosomal complex assembly. Each is linked with OOSP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OOSP3-to-partner and partner-to-OOSP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via homologous recombination grouped by OOSP3-low versus OOSP3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OOSP3→partner) and Y-score (partner→OOSP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Double-strand break repair via homologous recombination →	+0.043	+0.055	.005	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of embryonic development →	+0.056	+0.030	<.001	.002	3	4
LUNG_SCLC	Spliceosomal complex assembly →	+0.060	+0.043	.006	.002	3	4
LUNG_NSCLC_LUSC	Isoprenoid metabolic process →	-0.087	-0.046	.004	.007	3	4
LUNG_SCLC	Cytosolic ciliogenesis →	+0.133	+0.069	<.001	.001	3	4
LUNG_SCLC	Regulation of metaphase plate congression →	+0.084	+0.042	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,121 associations by consensus.

Double-strand break repair via homologous recombination by OOSP3 expression — LUNG_SCLC

Explore this box plot interactively →