OOSP2

Across TCGA cell cohorts, OOSP2 RNA expression is significantly associated with the mutation status of many other genes, with 137 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible OOSP2-associated genes across cancer lineages are HERC2, YLPM1, and KLRG2. Each is linked with OOSP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OOSP2-to-partner and partner-to-OOSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HERC2 grouped by OOSP2-low versus OOSP2-high in BONE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OOSP2→partner) and Y-score (partner→OOSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	HERC2 →	+2.807	+0.006	.006	.001	3	2
BREAST	YLPM1 →	+4.781	+0.017	.003	<.001	3	2
BREAST	KLRG2 →	+4.196	+0.013	.006	<.001	3	2
SOFT_TISSUE	MAP3K10 →	+5.977	+0.186	.001	<.001	3	1
SOFT_TISSUE	AHCTF1 →	+5.977	+0.186	.001	<.001	3	1
SOFT_TISSUE	FGD5 →	+3.977	+0.093	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 137 associations by consensus.

HERC2 by OOSP2 expression — BONE

Explore this box plot interactively →