Across TCGA patient cohorts, OOEP mutation is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OOEP-associated genes across cancer lineages are NCAPH2, UFD1, and MIR7849. Each is linked with OOEP in more than 1 cancer types. Because this analysis shows association rather than direction, both OOEP-to-partner and partner-to-OOEP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OOEP→partner) and Y-score (partner→OOEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.631	+3.475	<.001	.002	3	2
UCEC	UFD1 →	+0.531	+3.483	<.001	.002	3	2
SKCM	MIR7849 →	+0.316	+2.551	<.001	.003	3	2
COAD	SPATA31E3P →	+0.004	+5.142	<.001	.002	3	2
UCEC	CIDECP1 →	+0.430	+3.338	.001	.005	3	2
UCEC	LONP1 →	+0.645	+3.234	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

Exploration

OOEP survival (RNA) · tumor vs normal (RNA) · all OOEP data types