Across TCGA cell cohorts, OOEP mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OOEP-associated genes across cancer lineages are TMEM235, KLF18, and CD300H. Each is linked with OOEP in more than 1 cancer types. Because this analysis shows association rather than direction, both OOEP-to-partner and partner-to-OOEP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OOEP→partner) and Y-score (partner→OOEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMEM235 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	KLF18 →	+0.012	+4.930	<.001	.001	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

OOEP survival (RNA) · tumor vs normal (RNA) · all OOEP data types