Across TCGA patient cohorts, ONECUT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,192 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ONECUT3-associated GO terms across cancer lineages are Peptidyl-lysine modification, Protein methylation, and Positive regulation of chromosome organization. Each is linked with ONECUT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ONECUT3-to-partner and partner-to-ONECUT3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ONECUT3→partner) and Y-score (partner→ONECUT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Peptidyl-lysine modification →	+0.036	+0.077	<.001	<.001	3	11
KIRC	Protein methylation →	+0.041	+0.079	<.001	<.001	3	11
KIRC	Positive regulation of chromosome organization →	+0.039	+0.073	<.001	<.001	3	10
KIRC	Regulation of DNA repair →	+0.035	+0.078	<.001	<.001	3	10
KIRC	Positive regulation of DNA metabolic process →	+0.037	+0.082	<.001	<.001	3	10
KIRC	U2-type prespliceosome assembly →	+0.048	+0.075	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,192 associations by consensus.

Exploration

ONECUT3 survival (RNA) · tumor vs normal (RNA) · all ONECUT3 data types