OMP

Across TCGA pan-cancer cohorts, OMP Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OMP data layer compared with 25 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OMP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OMP expression acts as an unfavorable survival marker.

HNSC, STAD, and LIHC are the cancer types where OMP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.526	0.751	<.001	40	view →
STAD	OS	Median	All	0.192	0.669	<.001	24	view →
LIHC	OS	Median	All	0.028	0.777	<.001	24	view →
LUSC	OS	Median	II,III,IV	0.112	0.743	<.001	24	view →
UCEC	OS	Median	III,IV	0.061	0.588	.018	18	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OMP–HNSC (OS)

Open the HNSC breakdown →