OMP

Across TCGA patient cohorts, OMP RNA expression is significantly associated with the go_rna of many other GO terms, with 7,119 significant associations in total. OV shows the largest number of these associations.

The most reproducible OMP-associated GO terms across cancer lineages are Cytokinesis, Protein acylation, and Cytoskeleton-dependent cytokinesis. Each is linked with OMP in more than 23 cancer types. Because this analysis shows association rather than direction, both OMP-to-partner and partner-to-OMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytokinesis grouped by OMP-low versus OMP-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OMP→partner) and Y-score (partner→OMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Cytokinesis →	+0.067	+0.421	<.001	<.001	3	24
SCLC	Protein acylation →	+0.053	+0.452	.001	<.001	3	23
THYM	Cytoskeleton-dependent cytokinesis →	+0.047	+0.199	<.001	<.001	3	23
SCLC	Regulation of DNA repair →	+0.039	+0.335	.004	.006	2	24
ESCA	Autophagosome maturation →	+0.041	+0.729	<.001	<.001	3	22
UCS	Regulation of telomere maintenance via telomere lengthening →	+0.048	+0.433	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,119 associations by consensus.

Cytokinesis by OMP expression — SCLC

Explore this box plot interactively →