OMP

Across TCGA cell cohorts, OMP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,680 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OMP-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Regulation of intracellular protein transport. Each is linked with OMP in more than 8 cancer types. Because this analysis shows association rather than direction, both OMP-to-partner and partner-to-OMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by OMP-low versus OMP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OMP→partner) and Y-score (partner→OMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.058	+0.204	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.056	+0.132	<.001	.002	3	8
SOFT_TISSUE	Regulation of intracellular protein transport →	+0.042	+0.132	<.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.093	+0.123	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular transport →	+0.051	+0.136	<.001	.001	3	7
SOFT_TISSUE	Positive regulation of intracellular transport →	+0.055	+0.162	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,680 associations by consensus.

Endosomal transport by OMP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →