OMG

Across TCGA cell cohorts, OMG RNA expression is significantly associated with the go_rna of many other GO terms, with 3,312 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OMG-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Regulation of cellular response to heat, and Protein polymerization. Each is linked with OMG in more than 8 cancer types. Because this analysis shows association rather than direction, both OMG-to-partner and partner-to-OMG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cilium assembly grouped by OMG-low versus OMG-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OMG→partner) and Y-score (partner→OMG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of cilium assembly →	+0.059	+0.436	<.001	<.001	3	9
PANCREAS	Regulation of cellular response to heat →	+0.085	+0.151	<.001	.001	3	8
BLOOD_Leukemia	Protein polymerization →	+0.070	+0.537	<.001	<.001	3	8
URINARY_TRACT	mRNA 5'-splice site recognition →	+0.109	+0.178	.009	.003	3	8
STOMACH	Protein localization to cytoskeleton →	+0.064	+0.222	.004	.008	3	8
URINARY_TRACT	mRNA splice site recognition →	+0.116	+0.133	.002	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,312 associations by consensus.

Negative regulation of cilium assembly by OMG expression — BLOOD_Leukemia

Explore this box plot interactively →