OMA1

Across TCGA patient cohorts, OMA1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,444 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible OMA1-associated genes across cancer lineages are SEC23A, PGBD1, and ITGB1. Each is linked with OMA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OMA1-to-partner and partner-to-OMA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OMA1 versus SEC23A in OV, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OMA1→partner) and Y-score (partner→OMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC23A →	-0.586	-0.396	.003	.002	3	6
OV	PGBD1 →	-0.976	-0.564	<.001	<.001	3	6
OV	ITGB1 →	-0.605	-0.340	.002	.004	3	6
GBM	CYTOR →	-0.523	-0.306	.003	.002	3	6
OV	MEIS3 →	-0.771	-0.350	.006	.004	3	5
OV	LOX →	-0.984	-0.336	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,444 associations by consensus.

OMA1 vs SEC23A — OV

Explore this scatter interactively →