OMA1

Across TCGA patient cohorts, OMA1 mutation is significantly associated with the RNA expression of many other genes, with 692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OMA1-associated genes across cancer lineages are MIR1302-5, RNU6-679P, and RN7SKP3. Each is linked with OMA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OMA1-to-partner and partner-to-OMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1302-5 grouped by OMA1-low versus OMA1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OMA1→partner) and Y-score (partner→OMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR1302-5 →	+0.139	+4.199	<.001	.009	3	2
LUAD	RNU6-679P →	+0.584	+4.481	.001	.009	3	2
LUAD	RN7SKP3 →	+0.194	+5.087	<.001	.004	3	2
BLCA	NMNAT1P1 →	+0.112	+5.588	<.001	.004	3	1
BLCA	RN7SL199P →	+0.162	+6.814	<.001	<.001	3	1
COAD	KRTAP19-1 →	+0.085	+4.595	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 692 associations by consensus.

MIR1302-5 by OMA1 expression — SKCM

Explore this box plot interactively →