OMA1

Across TCGA cell cohorts, OMA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,003 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OMA1-associated GO terms across cancer lineages are Mitochondrial inner membrane fusion, Regulation of cristae formation, and Response to dietary excess. Each is linked with OMA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both OMA1-to-partner and partner-to-OMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial inner membrane fusion grouped by OMA1-low versus OMA1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OMA1→partner) and Y-score (partner→OMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitochondrial inner membrane fusion →	+0.173	+0.960	<.001	<.001	3	18
URINARY_TRACT	Regulation of cristae formation →	+0.173	+1.549	<.001	<.001	3	14
URINARY_TRACT	Response to dietary excess →	+0.142	+0.979	<.001	<.001	3	12
BREAST	Diet induced thermogenesis →	+0.493	+0.781	.005	<.001	3	11
OESOPHAGUS	Carboxylic acid catabolic process →	+0.064	+0.627	<.001	<.001	3	11
OESOPHAGUS	Organic acid catabolic process →	+0.064	+0.627	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,003 associations by consensus.

Mitochondrial inner membrane fusion by OMA1 expression — SKIN

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