OLR1

Across TCGA pan-cancer cohorts, OLR1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OLR1 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OLR1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated OLR1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where OLR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	1.000	0.132	.024	23	view →
PDAC	OS	Tertile	II,III,IV	0.246	0.856	.001	22	view →
LUAD	OS	Median	III,IV	0.330	0.791	.004	18	view →
GBM	DFS	Tertile	All	0.323	0.875	.002	9	view →
LSCC	OS	Tertile	All	1.000	0.599	.019	3	view →
UCEC	DFS	Median	All	0.803	0.972	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OLR1–HNSC (OS)

Open the HNSC breakdown →