OLR1

Across TCGA cell cohorts, OLR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,508 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OLR1-associated GO terms across cancer lineages are Positive regulation of tumor necrosis factor-mediated signaling pathway, Regulation of cytokine-mediated signaling pathway, and Negative regulation of RNA catabolic process. Each is linked with OLR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both OLR1-to-partner and partner-to-OLR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of tumor necrosis factor-mediated signaling pathway grouped by OLR1-low versus OLR1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OLR1→partner) and Y-score (partner→OLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of tumor necrosis factor-mediated signaling pathway →	+0.150	+3.497	<.001	.001	3	8
OESOPHAGUS	Regulation of cytokine-mediated signaling pathway →	+0.102	+4.465	<.001	<.001	3	8
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.062	+2.642	.005	.005	3	8
BONE	Positive regulation of plasma membrane repair →	+0.207	+0.789	.002	.008	3	8
STOMACH	Neurotransmitter secretion →	-0.080	-2.417	.001	.003	3	8
STOMACH	Signal release from synapse →	-0.080	-2.417	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,508 associations by consensus.

Positive regulation of tumor necrosis factor-mediated signaling pathway by OLR1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →