OLR1

Across TCGA cell cohorts, OLR1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OLR1-associated genes across cancer lineages are LALBA, OR11H1, and OR4K2. Each is linked with OLR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLR1-to-partner and partner-to-OLR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LALBA grouped by OLR1-low versus OLR1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLR1→partner) and Y-score (partner→OLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LALBA →	+0.047	+4.977	<.001	.007	3	1
BLOOD_Leukemia	OR11H1 →	+0.097	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR4K2 →	+0.042	+5.969	<.001	.001	3	1
BLOOD_Leukemia	PRORY →	+0.173	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR11G2 →	+0.392	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR11H2 →	+0.060	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

LALBA by OLR1 expression — SKIN

Explore this box plot interactively →