Across TCGA patient cohorts, OLIG2 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OLIG2-associated genes across cancer lineages are ERK2, ASNS, and C-Raf. Each is linked with OLIG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLIG2-to-partner and partner-to-OLIG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLIG2→partner) and Y-score (partner→OLIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.224	+3.169	.004	.018	3	2
UCEC	ASNS →	+0.479	+2.000	.001	.030	3	2
UCEC	C-Raf →	+0.191	+2.584	.001	.010	3	2
UCEC	EGFR_pY1068 →	-0.219	-2.321	.034	.006	3	1
UCEC	A-Raf_pS299 →	-0.156	-3.459	.001	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.137	-2.797	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

OLIG2 survival (RNA) · tumor vs normal (RNA) · all OLIG2 data types