Across TCGA cell cohorts, OLIG2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OLIG2-associated genes across cancer lineages are MYF5, CCER1, and DAOA. Each is linked with OLIG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLIG2-to-partner and partner-to-OLIG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLIG2→partner) and Y-score (partner→OLIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MYF5 →	+0.567	+4.321	<.001	.009	3	1
CNS	CCER1 →	+0.012	+4.754	<.001	.005	3	1
BLOOD_Leukemia	DAOA →	+0.034	+4.539	<.001	.007	3	1
BLOOD_Leukemia	KRTDAP →	+0.114	+4.276	<.001	.007	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1
LARGE_INTESTINE	CST9L →	+0.011	+3.562	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

OLIG2 survival (RNA) · tumor vs normal (RNA) · all OLIG2 data types