Across TCGA pan-cancer cohorts, OLFML1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated OLFML1 data layer compared with 22 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher OLFML1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OLFML1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BLCA and UCEC are the cancer types where OLFML1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	IV	0.090	0.469	.009	12	view →
UCEC	DFS	Median	All	0.955	0.628	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: OLFML1 tumor-vs-normal RNA expression · all OLFML1 data types