Across TCGA patient cohorts, OLFML1 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OLFML1-associated genes across cancer lineages are eEF2, eIF4E, and ERK2. Each is linked with OLFML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLFML1-to-partner and partner-to-OLFML1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML1→partner) and Y-score (partner→OLFML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.335	+2.321	.017	.033	3	1
UCEC	eIF4E →	+0.190	+3.013	.021	.018	3	1
UCEC	ERK2 →	+0.213	+2.000	.004	.030	3	1
UCEC	FOXO3a_pS318_S321 →	-0.104	-2.449	.033	.019	3	1
UCEC	GSK3-a-b →	+0.119	+3.459	.024	.005	3	1
UCEC	Ku80 →	+0.185	+2.013	.045	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

OLFML1 survival (RNA) · tumor vs normal (RNA) · all OLFML1 data types