OLFML1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OLFML1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OLFML1-associated genes across cancer lineages are OR4M1, BEND2, and HNRNPCL4. Each is linked with OLFML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLFML1-to-partner and partner-to-OLFML1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML1→partner) and Y-score (partner→OLFML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADOR4M1 →+0.010+5.266<.001.00131
LUNG_NSCLC_LUADBEND2 →+0.016+4.544<.001.00331
LARGE_INTESTINEHNRNPCL4 →+0.071+3.793<.001.00731
LARGE_INTESTINECD300H →+0.044+5.000<.001<.00131
BLOOD_LeukemiaODF4 →+0.043+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration