Across TCGA cell cohorts, OLFML1 mutation is significantly associated with the mutation status of many other genes, with 739 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OLFML1-associated genes across cancer lineages are USP28, PAPPA, and VPS13A. Each is linked with OLFML1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OLFML1-to-partner and partner-to-OLFML1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML1→partner) and Y-score (partner→OLFML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	USP28 →	+5.392	+4.824	.004	.004	1	3
LARGE_INTESTINE	PAPPA →	+2.159	+3.807	.007	.007	1	3
LUNG_NSCLC_LUAD	VPS13A →	+2.754	+4.189	.008	.008	1	2
LUNG_NSCLC_LUAD	ZKSCAN8 →	+5.339	+4.772	.004	.004	1	2
LUNG_NSCLC_LUAD	FER1L6 →	+2.924	+4.334	.006	.006	1	2
BLOOD_Lymphoma	IKZF1 →	+5.014	+5.584	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 739 associations by consensus.

Exploration

OLFML1 survival (RNA) · tumor vs normal (RNA) · all OLFML1 data types