OLFM4

Across TCGA patient cohorts, OLFM4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,636 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OLFM4-associated genes across cancer lineages are CEACAM3, ADGRG3, and ADGRE3. Each is linked with OLFM4 in more than 6 cancer types. Because this analysis shows association rather than direction, both OLFM4-to-partner and partner-to-OLFM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OLFM4 versus CEACAM3 in LUAD, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFM4→partner) and Y-score (partner→OLFM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CEACAM3 →	+0.718	+1.489	<.001	<.001	3	7
LSCC	ADGRG3 →	+0.931	+1.100	<.001	<.001	3	7
LSCC	ADGRE3 →	+0.725	+1.012	<.001	<.001	3	6
GBM	CXCL3 →	+1.247	+1.205	<.001	<.001	3	6
CCRCC	HCAR2 →	+0.924	+0.860	.004	.006	3	6
HNSC	FCAR →	+0.922	+1.159	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,636 associations by consensus.

OLFM4 vs CEACAM3 — LUAD

Explore this scatter interactively →