OLFM2

Across TCGA patient cohorts, OLFM2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,556 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OLFM2-associated genes across cancer lineages are WASF3, GSPT2, and SLC49A4. Each is linked with OLFM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OLFM2-to-partner and partner-to-OLFM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OLFM2 versus WASF3 in BRCA, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFM2→partner) and Y-score (partner→OLFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WASF3 →	+1.765	+1.260	<.001	.002	3	3
BRCA	GSPT2 →	+2.070	+1.185	.005	.003	3	3
LSCC	SLC49A4 →	+0.769	+0.711	.009	.003	3	2
PDAC	ERCC2 →	+0.393	+0.516	.001	.004	3	2
HNSC	THBS4 →	+2.597	+0.606	.002	.007	3	2
GBM	ALDH6A1 →	+0.434	+0.547	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,556 associations by consensus.

OLFM2 vs WASF3 — BRCA

Explore this scatter interactively →