OLFM2

Across TCGA cell cohorts, OLFM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,408 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OLFM2-associated GO terms across cancer lineages are Regulation of potassium ion transport, Positive regulation of potassium ion transport, and Regulation of postsynaptic membrane potential. Each is linked with OLFM2 in more than 10 cancer types. Because this analysis shows association rather than direction, both OLFM2-to-partner and partner-to-OLFM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of potassium ion transport grouped by OLFM2-low versus OLFM2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFM2→partner) and Y-score (partner→OLFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of potassium ion transport →	-0.143	-3.706	<.001	<.001	3	11
BONE	Positive regulation of potassium ion transport →	-0.161	-3.503	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of postsynaptic membrane potential →	-0.089	-0.384	<.001	<.001	3	10
SOFT_TISSUE	Regulation of cytosolic calcium ion concentration →	-0.087	-2.345	.002	.002	3	10
BONE	Positive regulation of DNA repair →	+0.057	+2.744	<.001	<.001	3	10
BREAST	Cytoskeleton-dependent cytokinesis →	+0.054	+2.282	.007	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,408 associations by consensus.

Regulation of potassium ion transport by OLFM2 expression — BONE

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