OLA1

Across TCGA pan-cancer cohorts, OLA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OLA1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher OLA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated OLA1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, GBM, and LUAD are the cancer types where OLA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.988	0.857	.005	22	view →
GBM	OS	Quartile	All	0.446	0.724	.004	18	view →
LUAD	OS	Tertile	All	0.659	1.000	.004	9	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OLA1–LSCC (DFS)

Open the LSCC breakdown →