OLA1

Across TCGA patient cohorts, OLA1 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OLA1-associated genes across cancer lineages are eEF2, ASNS, and EGFR_pY1068. Each is linked with OLA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLA1-to-partner and partner-to-OLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by OLA1-low versus OLA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLA1→partner) and Y-score (partner→OLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.444	+1.906	.001	.016	3	2
UCEC	ASNS →	+0.465	+2.321	.001	.034	3	2
UCEC	EGFR_pY1068 →	-0.355	-4.169	<.001	<.001	2	2
UCEC	GATA6 →	-0.147	-3.155	.018	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.216	-2.807	.001	.003	3	1
UCEC	Ku80 →	+0.285	+2.428	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

eEF2 by OLA1 expression — UCEC

Explore this box plot interactively →