OLA1

Across TCGA cell cohorts, OLA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,692 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OLA1-associated GO terms across cancer lineages are DNA replication initiation, Mitochondrial RNA modification, and Negative regulation of nuclear division. Each is linked with OLA1 in more than 13 cancer types. Because this analysis shows association rather than direction, both OLA1-to-partner and partner-to-OLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by OLA1-low versus OLA1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OLA1→partner) and Y-score (partner→OLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication initiation →	+0.178	+0.717	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Mitochondrial RNA modification →	+0.100	+0.757	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.152	+1.090	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic nuclear division →	+0.168	+1.113	.001	<.001	3	12
BREAST	Mitochondrial tRNA processing →	+0.104	+0.740	<.001	<.001	3	12
BLOOD_Myeloma	Centromeric sister chromatid cohesion →	+0.166	+0.917	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,692 associations by consensus.

DNA replication initiation by OLA1 expression — PANCREAS

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