OLA1

Across TCGA cell cohorts, OLA1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OLA1-associated genes across cancer lineages are TNP1, ZNF831, and CENPVL1. Each is linked with OLA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLA1-to-partner and partner-to-OLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by OLA1-low versus OLA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLA1→partner) and Y-score (partner→OLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF831 →	+0.013	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.211	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	CSN1S1 →	+0.028	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TNP1 by OLA1 expression — LARGE_INTESTINE

Explore this box plot interactively →