OIT3

Across TCGA cell cohorts, OIT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,018 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible OIT3-associated GO terms across cancer lineages are Cellular response to calcium ion starvation, Regulation of RNA export from nucleus, and Canonical NF-kappaB signal transduction. Each is linked with OIT3 in more than 4 cancer types. Because this analysis shows association rather than direction, both OIT3-to-partner and partner-to-OIT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to calcium ion starvation grouped by OIT3-low versus OIT3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OIT3→partner) and Y-score (partner→OIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cellular response to calcium ion starvation →	+0.154	+0.052	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA export from nucleus →	+0.058	+0.100	.004	.002	3	5
LUNG_NSCLC_LUSC	Canonical NF-kappaB signal transduction →	+0.089	+0.047	.003	.008	3	5
LARGE_INTESTINE	Protein folding in endoplasmic reticulum →	+0.046	+0.131	.006	.004	3	5
CNS	DNA repair-dependent chromatin remodeling →	+0.052	+0.037	.002	.009	3	4
CNS	Positive regulation of DNA repair →	+0.026	+0.048	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,018 associations by consensus.

Cellular response to calcium ion starvation by OIT3 expression — SOFT_TISSUE

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