OIP5

Across TCGA patient cohorts, OIP5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OIP5-associated genes across cancer lineages are MPP, Th1 cells, and MEP. Each is linked with OIP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OIP5-to-partner and partner-to-OIP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by OIP5-low versus OIP5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OIP5→partner) and Y-score (partner→OIP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MPP →	+0.025	+3.930	.020	.004	3	1
UCEC	Th1 cells →	+0.114	+2.321	.015	.036	3	1
UCEC	MEP →	+0.046	+2.332	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MPP by OIP5 expression — BLCA

Explore this box plot interactively →