OIP5

Across TCGA cell cohorts, OIP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,087 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OIP5-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Mitotic nuclear division, and Protein localization to condensed chromosome. Each is linked with OIP5 in more than 18 cancer types. Because this analysis shows association rather than direction, both OIP5-to-partner and partner-to-OIP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle process grouped by OIP5-low versus OIP5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OIP5→partner) and Y-score (partner→OIP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of cell cycle process →	+0.107	+1.611	<.001	<.001	3	19
BLOOD_Myeloma	Mitotic nuclear division →	+0.105	+1.501	<.001	<.001	3	19
OESOPHAGUS	Protein localization to condensed chromosome →	+0.159	+0.968	.001	<.001	3	19
BONE	CENP-A containing chromatin assembly →	+0.221	+1.398	<.001	<.001	3	19
BLOOD_Myeloma	Protein localization to kinetochore →	+0.165	+1.562	<.001	<.001	3	19
BONE	Interstrand cross-link repair →	+0.093	+1.304	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,087 associations by consensus.

Positive regulation of cell cycle process by OIP5 expression — BLOOD_Myeloma

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