OIP5-AS1

Across TCGA pan-cancer cohorts, OIP5-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated OIP5-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher OIP5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OIP5-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

UVM, ACC, and KIRC are the cancer types where OIP5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.252	0.716	.001	77	view →
ACC	DFS	Median	All	0.257	0.655	<.001	71	view →
KIRC	DFS	Tertile	All	0.850	0.680	.002	41	view →
HNSC	DFS	Tertile	All	0.801	0.664	.003	27	view →
BLCA	OS	Median	IV	0.153	0.401	.005	26	view →
KICH	DFS	Quartile	All	0.570	1.000	.001	26	view →
COAD	OS	Quartile	III,IV	0.476	0.815	.001	21	view →
PCPG	OS	Quartile	All	0.757	1.000	.024	18	view →
CHOL	DFS	Tertile	All	0.610	0.293	.010	15	view →
THYM	DFS	Tertile	All	1.000	0.632	.009	13	view →
GBM	DFS	Quartile	All	0.467	0.185	.003	12	view →
UCS	DFS	Tertile	IV	0.857	0.361	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

OIP5-AS1–UVM (DFS)

Open the UVM breakdown →