OGN

Across TCGA cell cohorts, OGN mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OGN-associated genes across cancer lineages are VN1R3, ADIG, and MT1HL1. Each is linked with OGN in more than 1 cancer types. Because this analysis shows association rather than direction, both OGN-to-partner and partner-to-OGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R3 grouped by OGN-low versus OGN-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGN→partner) and Y-score (partner→OGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	VN1R3 →	+0.021	+5.539	.006	.003	3	1
BLOOD_Leukemia	ADIG →	+0.030	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	MT1HL1 →	+0.237	+4.922	.006	.009	3	1
BLOOD_Leukemia	OR10G4 →	+0.021	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

VN1R3 by OGN expression — BLOOD_Leukemia

Explore this box plot interactively →