OGFRP1

Across TCGA pan-cancer cohorts, OGFRP1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of OGFRP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OGFRP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OGFRP1 is over-expressed in tumor.

HNSC, BLCA, and LUAD are the cancer types where OGFRP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OGFRP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.972	<.001	11	view →
BLCA	All	III,IV	+0.728	<.001	10	view →
LUAD	Male	II,III,IV	+0.914	<.001	9	view →
LUSC	Male	II,III,IV	+1.435	<.001	8	view →
COAD	Female	All	+0.640	<.001	8	view →
STAD	All	II,III,IV	+0.653	<.001	7	view →
KIRP	All	II,III,IV	+0.486	.005	6	view →
BRCA	All	All	+0.241	<.001	4	view →
READ	Female	All	+0.978	.002	2	view →
PRAD	All	All	+0.468	<.001	2	view →
KICH	All	II,III,IV	+0.256	.039	2	view →
KIRC	All	All	+0.165	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

OGFRP1–HNSC

Open the HNSC breakdown →