OGFRL1

Across TCGA pan-cancer cohorts, OGFRL1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OGFRL1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher OGFRL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated OGFRL1 expression acts as an unfavorable survival marker.

PDAC, CCRCC, and GBM are the cancer types where OGFRL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.533	0.939	<.001	85	view →
CCRCC	OS	Median	III,IV	0.133	0.989	.013	10	view →
GBM	DFS	Median	All	0.266	0.475	.024	6	view →
HNSC	DFS	Quartile	IV	0.642	0.887	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OGFRL1–PDAC (OS)

Open the PDAC breakdown →