OGFRL1

Across TCGA cell cohorts, OGFRL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,531 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OGFRL1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cell-substrate junction organization, and Nucleotide-excision repair. Each is linked with OGFRL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both OGFRL1-to-partner and partner-to-OGFRL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by OGFRL1-low versus OGFRL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFRL1→partner) and Y-score (partner→OGFRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.200	+1.776	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.209	+2.697	<.001	<.001	3	12
OESOPHAGUS	Nucleotide-excision repair →	+0.079	+1.312	<.001	<.001	3	11
BONE	Regulation of cell-matrix adhesion →	+0.149	+1.705	<.001	<.001	3	11
BONE	Negative regulation of Rho protein signal transduction →	+0.167	+1.531	<.001	<.001	3	11
PANCREAS	Melanosome assembly →	+0.087	+1.442	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,531 associations by consensus.

Positive regulation of focal adhesion assembly by OGFRL1 expression — BONE

Explore this box plot interactively →