OGFOD2

Across TCGA cell cohorts, OGFOD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,900 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OGFOD2-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Positive regulation of intracellular steroid hormone receptor signaling pathway, and CAMKK-AMPK signaling cascade. Each is linked with OGFOD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both OGFOD2-to-partner and partner-to-OGFOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by OGFOD2-low versus OGFOD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD2→partner) and Y-score (partner→OGFOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.162	+1.039	<.001	<.001	3	12
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.197	+0.928	<.001	<.001	3	12
STOMACH	CAMKK-AMPK signaling cascade →	+0.169	+0.950	.001	.001	3	11
BONE	Lipoprotein transport →	+0.137	+0.563	<.001	.007	3	11
SKIN	Lipoprotein localization →	+0.118	+0.689	<.001	<.001	3	11
BLOOD_Myeloma	Vacuole organization →	+0.053	+1.096	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,900 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by OGFOD2 expression — BONE

Explore this box plot interactively →