OGFOD2

Across TCGA cell cohorts, OGFOD2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OGFOD2-associated genes across cancer lineages are SMIM23, COX4I2, and USP29. Each is linked with OGFOD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD2-to-partner and partner-to-OGFOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM23 grouped by OGFOD2-low versus OGFOD2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD2→partner) and Y-score (partner→OGFOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SMIM23 →	+0.030	+6.569	<.001	<.001	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.095	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	USP29 →	+0.016	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP10-3 →	+0.032	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	GAGE12D →	+2.651	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

SMIM23 by OGFOD2 expression — BLOOD_Leukemia

Explore this box plot interactively →