OGFOD1P1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, OGFOD1P1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of OGFOD1P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where OGFOD1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types OGFOD1P1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, UCEC, and KIRC are the cancer types where OGFOD1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OGFOD1P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHMaleAll−0.295<.0017view →
UCECAllII,III,IV+0.172.0166view →
KIRCAllAll−0.069<.0016view →
KIRPAllIV+0.267.0123view →
THCAAllAll−0.060.0053view →
CHOLMaleAll+0.219.0352view →
LIHCMaleAll+0.037.0451view →
HNSCAllIII,IV+0.035.0331view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

OGFOD1P1–KICH

Tumor-vs-normal expression box plot for OGFOD1P1 RNA in KICH.

Open the KICH breakdown →

Exploration