OGFOD1

Across TCGA pan-cancer cohorts, OGFOD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OGFOD1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher OGFOD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated OGFOD1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

PDAC, CCRCC, and LUAD are the cancer types where OGFOD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.597	0.918	.005	44	view →
CCRCC	DFS	Median	III,IV	0.314	0.702	<.001	22	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.324	.003	17	view →
UCEC	DFS	Median	II,III,IV	0.882	0.518	.030	4	view →
LSCC	OS	Median	All	0.835	0.927	.038	3	view →
HNSC	OS	Median	All	0.992	0.942	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OGFOD1–PDAC (DFS)

Open the PDAC breakdown →