Across TCGA cell cohorts, OGDHL mutation is significantly associated with the RNA expression of many other genes, with 247 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OGDHL-associated genes across cancer lineages are PGK2, OR2D3, and OR4F15. Each is linked with OGDHL in more than 1 cancer types. Because this analysis shows association rather than direction, both OGDHL-to-partner and partner-to-OGDHL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGDHL→partner) and Y-score (partner→OGDHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PGK2 →	+0.028	+4.415	<.001	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	OR2D3 →	+0.040	+3.510	<.001	.007	3	2
BLOOD_Leukemia	OR4F15 →	+0.002	+2.786	<.001	.009	3	2
BLOOD_Leukemia	ELOA3CP →	+0.086	+3.011	.002	.002	3	2
CNS	CCR5 →	+0.074	+4.087	<.001	.004	3	2
OESOPHAGUS	SRARP →	+0.005	+3.115	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 247 associations by consensus.

Exploration

OGDHL survival (RNA) · tumor vs normal (RNA) · all OGDHL data types