Across TCGA patient cohorts, OGA RNA expression is significantly associated with the protein abundance of many other proteins, with 14,393 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OGA-associated proteins across cancer lineages are RPS6_S240, ARL3, and OGA_S364. Each is linked with OGA in more than 5 cancer types. Because this analysis shows association rather than direction, both OGA-to-partner and partner-to-OGA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OGA→partner) and Y-score (partner→OGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS6_S240 →	-0.694	-0.351	.001	<.001	2	6
GBM	ARL3 →	+0.348	+0.401	<.001	<.001	3	5
PDAC	OGA_S364 →	+0.638	+0.308	<.001	<.001	3	5
BRCA	GABPB1 →	+0.282	+0.492	.004	<.001	3	5
BRCA	VEZF1 →	+0.362	+0.445	.001	<.001	3	4
GBM	MOGS →	-0.313	-0.458	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,393 associations by consensus.

Exploration

OGA survival (RNA) · tumor vs normal (RNA) · all OGA data types