OFD1P6Y

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OFD1P6Y RNA expression is significantly associated with the go_rna of many other GO terms, with 1,471 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible OFD1P6Y-associated GO terms across cancer lineages are Positive regulation of RNA export from nucleus, Maturation of LSU-rRNA, and ESCRT complex disassembly. Each is linked with OFD1P6Y in more than 2 cancer types. Because this analysis shows association rather than direction, both OFD1P6Y-to-partner and partner-to-OFD1P6Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of RNA export from nucleus grouped by OFD1P6Y-low versus OFD1P6Y-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OFD1P6Y→partner) and Y-score (partner→OFD1P6Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAPositive regulation of RNA export from nucleus →+0.043+0.009<.001.00533
LAMLMaturation of LSU-rRNA →+0.047+0.012.001.00333
SKCMESCRT complex disassembly →+0.072+0.004<.001.00532
LAMLPostsynaptic modulation of chemical synaptic transmission →+0.044+0.015<.001.00232
COADActomyosin contractile ring organization →+0.068+0.001<.001.00232
LAMLCo-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →+0.043+0.010.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,471 associations by consensus.

Positive regulation of RNA export from nucleus by OFD1P6Y expression — ESCA

Box plot of Positive regulation of RNA export from nucleus in OFD1P6Y-low vs OFD1P6Y-high samples in ESCA.

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Exploration