OFD1P4Y

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OFD1P4Y RNA expression is significantly associated with the go_rna of many other GO terms, with 190 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible OFD1P4Y-associated GO terms across cancer lineages are Negative regulation of interleukin-1-mediated signaling pathway, Craniofacial suture morphogenesis, and Regulation of neuronal action potential. Each is linked with OFD1P4Y in more than 1 cancer types. Because this analysis shows association rather than direction, both OFD1P4Y-to-partner and partner-to-OFD1P4Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of interleukin-1-mediated signaling pathway grouped by OFD1P4Y-low versus OFD1P4Y-high in OV.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OFD1P4Y→partner) and Y-score (partner→OFD1P4Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVNegative regulation of interleukin-1-mediated signaling pathway →-0.047-0.006.001.00331
ESCACraniofacial suture morphogenesis →-0.065-0.009<.001<.00131
ESCARegulation of neuronal action potential →+0.131+0.013<.001.00231
ESCAAnterograde dendritic transport of neurotransmitter receptor complex →+0.083+0.009.002.00131
ESCACardiac muscle myoblast proliferation →+0.077+0.008.002.00331
ESCAPrimary amino compound metabolic process →+0.091+0.010<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 190 associations by consensus.

Negative regulation of interleukin-1-mediated signaling pathway by OFD1P4Y expression — OV

Box plot of Negative regulation of interleukin-1-mediated signaling pathway in OFD1P4Y-low vs OFD1P4Y-high samples in OV.

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Exploration