OFD1

Across TCGA cell cohorts, OFD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,674 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OFD1-associated GO terms across cancer lineages are Epithelial cilium movement involved in determination of left/right asymmetry, Sperm motility, and Flagellated sperm motility. Each is linked with OFD1 in more than 17 cancer types. Because this analysis shows association rather than direction, both OFD1-to-partner and partner-to-OFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cilium movement involved in determination of left/right asymmetry grouped by OFD1-low versus OFD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OFD1→partner) and Y-score (partner→OFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epithelial cilium movement involved in determination of left/right asymmetry →	+1.526	+1.029	<.001	<.001	3	18
OVARY	Sperm motility →	-0.091	-1.003	<.001	<.001	3	12
OVARY	Flagellated sperm motility →	-0.091	-1.003	<.001	<.001	3	12
OVARY	Cilium movement involved in cell motility →	-0.089	-0.959	<.001	.001	3	11
LUNG_SCLC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.112	+1.052	<.001	<.001	3	11
OVARY	Cilium or flagellum-dependent cell motility →	-0.086	-0.911	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,674 associations by consensus.

Epithelial cilium movement involved in determination of left/right asymmetry by OFD1 expression — BONE

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