OFCC1

Across TCGA cell cohorts, OFCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 938 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OFCC1-associated GO terms across cancer lineages are Positive regulation of cardiac muscle tissue growth, Regulation of cytokine-mediated signaling pathway, and Toll-like receptor 4 signaling pathway. Each is linked with OFCC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OFCC1-to-partner and partner-to-OFCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cardiac muscle tissue growth grouped by OFCC1-low versus OFCC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OFCC1→partner) and Y-score (partner→OFCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cardiac muscle tissue growth →	-0.124	-0.430	<.001	.003	2	6
BLOOD_Lymphoma	Regulation of cytokine-mediated signaling pathway →	+0.047	+0.297	<.001	.004	2	5
BLOOD_Myeloma	Toll-like receptor 4 signaling pathway →	+0.066	+0.325	.003	.004	3	4
PANCREAS	Insulin receptor signaling pathway →	+0.034	+0.251	.002	.008	3	4
SKIN	Establishment of vesicle localization →	+0.035	+0.280	<.001	.007	3	4
LUNG_NSCLC_LUAD	Positive regulation of protein deubiquitination →	+0.089	+0.252	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 938 associations by consensus.

Positive regulation of cardiac muscle tissue growth by OFCC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →